Neuroinflammation and its role in the pathogenesis of attention deficit hyperactivity disorder (literature review)

The article discusses the role of inflammatory reactions in formation attention deficit hyperactivity disorder (ADHD). Based on a wide and modern material, mechanisms development oxidative stress with free radicals are considered, which, turn, initiate cascade reactions. Inflammation factors analyzed detail, biomarkers neuroinflammation distinguished their changing neurotransmitter balance is revealed. Biomarkers isolated from patients ADHD give conflicting results some particular issues, which certainly require clarification. But general, it found that increased inflammation early stages brain seems to be associated phenotype. commonly believed hereditary disease; therefore, can expected have polymorphisms genes inflammation, illustrated range material. In addition, problems inducing traditional drugs for treatment ADHD: methylphenidate atomoxetine considered. prospects developing algorithms diagnosis noted.